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Major Areas of Research

  • T-cell and cytokine regulation of B-cell polyclonal activation
  • Stem cell transplantation for the treatment of autoimmune diseases
  • Mechanisms of tolerance induction and maintenance; role of cytokines
  • Clinical transplantation immunology, both solid organ and bone marrow transplantation; role of HLA and non-HLA polymorphisms
  • Molecular regulation of B-lymphocyte activation and death
  • Abnormal regulation of gene transcription in autoimmunity
  • Molecular biology and immunology of persistent viral infections in rheumatic diseases
  • Immune cell stimulation by bacterial DNA
  • Role of Gamma-Delta T-cells in Immune-Mediated Disease
  • Immuno-Oncology
  • Rheumatology educational curriculum development and testing