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Merry P. Mani, PhD

Director, Microstructure Imaging Lab
Assistant Professor of Radiology - Division of Neuroradiology

Contact Information

Primary Office
169 Newton Road
Iowa City, IA 52242


BTech, Electrical and Electronics Engineering, Kerala University, College of Engineering
MS, Electrical and Computer Engineering, University of Illinois
PhD, Electrical and Computer Engineering, University of Rochester
Postdoctoral Fellow, Magnetic Resonance Research Facility, University of Iowa

Research Summary

Pulse sequence design for efficient MR acquisition

Design of trajectories for optimal multi-dimensional sampling Cartesian, multi-shot, spiral, radial

Novel reconstruction methods for enabling new MR applications

Phase-compensated high resolution Diffusion MRI

Self-Calibrated reconstruction methods artifact correction

Continuous domain compressed sensing, discrete compressed sensing, dictionary based recovery


Aggarwal, H. K., Mani, M. P. & Jacob, M. (2019). MoDL: Model-Based Deep Learning Architecture for Inverse Problems. IEEE transactions on medical imaging, 38(2), 394-405. PMID: 30106719.

Balachandrasekaran, A., Mani, M. & Jacob, M. (2018). Calibration-free B0 correction of EPI data using structured low rank matrix recovery. IEEE transactions on medical imaging. PMID: 30334785.

Mani, M., Magnotta, V. & Jacob, M. (2018). A general algorithm for compensation of trajectory errors: Application to radial imaging. Magnetic resonance in medicine, 80(4), 1605-1613. PMID: 29493002.

Johnson, C. P., Christensen, G. E., Fiedorowicz, J. G., Mani, M., Shaffer, J. J., Magnotta, V. A. & Wemmie, J. A. (2018). Alterations of the cerebellum and basal ganglia in bipolar disorder mood states detected by quantitative T1? mapping. Bipolar Disorders, 20(4), 381-390. DOI: 10.1111/bdi.12581.

Mani, M., Jacob, M., Kelley, D. & Magnotta, V. (2017). Multi-shot sensitivity-encoded diffusion data recovery using structured low-rank matrix completion (MUSSELS). Magnetic resonance in medicine, 78(2), 494-507. PMID: 27550212.

Liao, C., Chen, Y., Cao, X., Chen, S., He, H., Mani, M., Jacob, M., Magnotta, V. & Zhong, J. (2017). Efficient parallel reconstruction for high resolution multishot spiral diffusion data with low rank constraint. Magnetic resonance in medicine, 77(3), 1359-1366. PMID: 26968846.

Mani, M., Magnotta, V., Kelley, D. & Jacob, M. (2016). Comprehensive reconstruction of multi-shot multi-channel diffusion data using mussels. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. (Vols. 2016-October). pp. 1107-1110. DOI: 10.1109/EMBC.2016.7590897.

Mani, M., Jacob, M., Magnotta, V. & Zhong, J. (2015). Fast iterative algorithm for the reconstruction of multishot non-cartesian diffusion data. Magnetic resonance in medicine, 74(4), 1086-94. PMID: 25323847.

Mani, M., Jacob, M., Guidon, A., Magnotta, V. & Zhong, J. (2015). Acceleration of high angular and spatial resolution diffusion imaging using compressed sensing with multichannel spiral data. Magnetic resonance in medicine, 73(1), 126-38. PMID: 24443248.

Daducci, A., Canales-Rodríguez, E. J., Descoteaux, M., Garyfallidis, E., Gur, Y., Lin, Y. C., Mani, M., Merlet, S., Paquette, M., Ramirez-Manzanares, A., Reisert, M., Reis Rodrigues, P., Sepehrband, F., Caruyer, E., Choupan, J., Deriche, R., Jacob, M., Menegaz, G., Prckovska, V., Rivera, M., Wiaux, Y. & Thiran, J. P. (2014). Quantitative comparison of reconstruction methods for intra-voxel fiber recovery from diffusion MRI. IEEE transactions on medical imaging, 33(2), 384-99. PMID: 24132007.

Dubose, L. E., Weng, T. B., Dubishar, K., Mani, M., Voss, M. W. & Pierce, G. L. (2014). Higher Aortic Stiffness and Carotid Systolic and Pulse Pressure Are Selectively Associated with Lower White Matter Integrity in The Genu and Frontal Cortex in Older Healthy Adults. Artery Research, 2014. DOI: 10.1016/j.artres.2014.09.028.

Bavelier, D., Achtman, R. L., Mani, M. & Föcker, J. (2012). Neural bases of selective attention in action video game players. Vision research, 61, 132-43. PMID: 21864560.